Smoking and Parkinson's Disease
- 1 August 1986
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 43 (8) , 774-778
- https://doi.org/10.1001/archneur.1986.00520080022014
Abstract
• We tested the hypothesis that the inverse association of smoking and Parkinson's disease (PD) results from a direct pharmacologic benefit of smoking on PD. We mailed questionnaires to the 32 000 members of the United Parkinson Foundation and searched for evidence of a doseresponse effect between increasing intensity of smoking and decreasing intensity of PD. Of the 6006 respondents, 3693 met our diagnostic criteria. Despite confining the analysis to subgroups where confounding effects would be minimized, we found no significant correlation between any measure of smoking and any measure of PD severity and conclude that smoking is probably not of benefit in preventing, delaying, or ameliorating PD.This publication has 3 references indexed in Scilit:
- The effects of nicotine on brain neurotransmitter systemsPharmacology & Therapeutics, 1982
- Accuracy of information on smoking habits provided on self-administered research questionnaires.American Journal of Public Health, 1981
- Comparison of biochemical and questionnaire estimates of tobacco exposurePreventive Medicine, 1979