IMMUNIZATION AGAINST FELINE CALICIVIRUS INFECTION

  • 1 January 1976
    • journal article
    • research article
    • Vol. 37  (3) , 275-278
Abstract
Cats (43) were vaccinated i.m. (2 doses, 27 and 30 days between doses) with the F-9 strain of feline calicivirus. There was no untoward response in any cat to the administration of the vaccinal virus. There was no spread of the virus from 20 vaccinated cats to nonvaccinated cats held in contact during the next 6 mo. The vaccinated cats developed serum-neutralizing antibodies that were increased further after the 2nd vaccination. The level of serum-neutralizing antibodies was related to the quantity of vaccinal virus administered. Twenty-three cats vaccinated with the F-9 strain were protected to a significant degree when challenge exposed to virulent calicivirus strain FPV-255.

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