Effects of Hadacidin on Human Tumors Grown in Eggs and Rats.
- 1 May 1962
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 110 (1) , 1-4
- https://doi.org/10.3181/00379727-110-27402
Abstract
Four transplantable human tumors (H. Ep. 3, H.S. 1, H. Ad. 1 and A-42) were grown on the CAM of chick embryos and used to determine the anti-tumor potential of hadacidin. There was consistent anti-tumor activity. When a comparison among the tumor types of their response to hadacidin was made, A-42 appeared to be consistently more sensitive to hadacidin than were the other types of tumors. Using two different routes of administration, intraperitoneal and per os, hadacidin inhibited the growth of H.S. 1 in the X-lrradiated and cortisone treated rat The positive results obtained in the mammalian host are further indications of the anti-tumor potentials of hadacidin.Keywords
This publication has 0 references indexed in Scilit: