One-Pot Synthesis of 1-Substituted Cyclopropanols from Carboxylic Acid Chlorides
- 1 January 1987
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1987 (06) , 584-586
- https://doi.org/10.1055/s-1987-28016
Abstract
The in situ generated chloromethyl-lithium reacts at -78°C to - 30°C with different acid chlorides (2:1 molar ratio) to afford, after lithiation with lithium powder, 1-substituted cyclopropanols.Keywords
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