4-Hydroxy-2-cyclopentenone: An Anti-Pseudomonas and Cytotoxic Component fromPassiflora tetrandra1
- 1 April 1991
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 57 (02) , 129-131
- https://doi.org/10.1055/s-2006-960048
Abstract
4-Hydroxy-2-cyclopentenone is responsible for the anti-bacterial activity of an extract of leaves from Passiflora tetrandra with minimum inhibitory doses (MID) of ca. 10 µg/disk against Escherichia coli, Bacillus subtilis, and Pseudomonas aeruginosa. 4-Hydroxy-2-cyclopentenone is also cytotoxic to P388 murine leukemia cells (IC50 of < 1 µg/ml).Keywords
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