OLIGOCLONAL IgG AND MEASLES ANTIBODY IN CSF OF MULTIPLE SCLEROSIS PATIENTS
- 29 January 2009
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 56 (2) , 153-158
- https://doi.org/10.1111/j.1600-0404.1977.tb01419.x
Abstract
CSF was obtained from 50 neurological patients, 26 of whom suffered from multiple sclerosis (MS). Agar gel electrophoresis and determination of anti-measles antibody titer were performed on the CSF samples. The frequency of elevated measles antibody titer was higher among the MS patients than among the patients with other neurological diseases. Oligoclonal Ig[immunoglobulin]G in CSF occurred more often among the MS patients than among the other neurological patients. An association between high measles antibody titer and the presence of oligoclonal IgG was observed in CSF from the MS patients and the patients with other neurological diseases. The nature of the correlation between the occurence of oligoclonal IgG and high measles antibody titer remains to be explained.This publication has 9 references indexed in Scilit:
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