Efficient visible light sensitisation of water-soluble near-infrared luminescent lanthanide complexes

Abstract
Fluorexon (4′,5′-bis[N,N-bis(carboxymethyl)aminomethyl]fluorescein) forms stable, water-soluble complexes with lanthanide ions. The complexes with neodymium(III), erbium(III) and ytterbium(III) display sensitised near-infrared lanthanide luminescence upon excitation of the fluorexon with visible light. The photosensitisation efficiency is very high (0.5–1.0) as a result of lanthanide-enhanced intersystem crossing in the sensitising chromophore and rapid intracomplex energy transfer. The overall luminescence quantum yields, however, are low (2 × 10−4–5 × 10−3) due to nonradiative deactivation of the excited lanthanide ion.

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