THE DISTRIBUTION OF ADRENERGIC VASODILATORS IN THE RAT

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Abstract
Vasopressor responses to (1) small amts. of epinephrin in normal white rats, (2) small doses of epinephrin in rats with the suprarenal medulla eliminated, and (3) epinephrin revealed in normal rats after treatment with ergotamin, were studied after reduction of the peripheral or of the splanchnic circulation by ligation. It was concluded that in the rat, as in the cat, adrenergic vasoconstrictors are more abundantly distributed to the splanchnic area than to the peripheral area; but that the rat, unlike the cat, has a significant distribution of adrenergic vasodilators to both regions. The biological significance of this apparent interspecific difference is discussed.

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