A Comparison of the Progression Rate to Acquired Immunodeficiency Syndrome between Intravenous Drug Users and Homosexual Men
- 1 December 1994
- journal article
- research article
- Published by SAGE Publications in Scandinavian Journal of Social Medicine
- Vol. 22 (4) , 309-314
- https://doi.org/10.1177/140349489402200411
Abstract
In order to study differences in progression to Acquired Immunodeficiency Syndrome (AIDS) between risk groups, 205 homosexual men and 185 intravenous drug users (IVDUs) were followed from diagnosed seropositivity for Human Immunodeficiency Virus Type-1 (HIV) for a mean period of 46 months (range 1–88 months). Seven (4%) IVDUs and 55 homosexual men (27%) were diagnosed with AIDS during the follow-up period. The probability of being AIDS-free four years after diagnosed HIV positivity was 0.96 for IVDUs (SE 0.02) and 0.73 (SE 0.04) for homosexual men (p < 0.001, log rank test). When controlling for age and gender, the relative risk of AIDS progression for homosexual men was 9.1 (3.5–24.1, 95% confidence interval) as compared with IVDUs. Even when 24 months of follow-up time without progression were added for all homosexual men, assuming that the epidemic started two years earlier in this group, the relative risk of progression was 5.4 (2.1–14.4, 95% confidence interval) for homosexual men.Keywords
This publication has 16 references indexed in Scilit:
- Estimation of the Acquired Immunodeficiency Syndrome Incubation Period in Intravenous Drug Users: A Comparison with Male HomosexualsAmerican Journal of Epidemiology, 1992
- AIDS incubation in 1891 HIV seroconverters from different exposure groupsAIDS, 1990
- Impact of the human immunodeficiency virus epidemic on mortality trends in young men, United States.American Journal of Public Health, 1990
- The Early Introduction of HIV Infection among Norwegians at Highest RiskScandinavian Journal of Infectious Diseases, 1990
- ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS)-FREE TIME AFTER HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) SEROCONVERSION IN HOMOSEXUAL MENAmerican Journal of Epidemiology, 1989
- The natural history of HIV infection in intravenous drug usersAIDS, 1989
- A Larger Spectrum of Severe HIV-1—Related Disease in Intravenous Drug Users in New York CityScience, 1988
- Increased risk of bacterial pneumonia in HIV-infected intravenous drug users without AIDSAIDS, 1988
- Trends in mortality statistics in England and Wales with particular reference to AIDS from 1984 to April 1987BMJ, 1988
- PREVALENCE, INCIDENCE AND DURATIONAmerican Journal of Epidemiology, 1980