L-Lysine Monohydrochloride

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Abstract
THE usefulness of chloruretic, acidifying agents before the administration of mercurial diuretics is well established,1 since they have been shown to enhance the intensity of diuresis after injection of a mercurial agent and to restore responsiveness in patients refractory to mercurial diuretics, particularly those who are refractory because of hypochloremic alkalosis resulting from repeated administration of such diuretics.2 3 4 Recent reports have indicated that refractory heart failure associated with chronic "dilutional hyponatremia" or "low-salt syndrome" can be treated by vigorous acidification before the use of a mercurial diuretic.5 The drug most commonly employed for this purpose is ammonium chloride, which has . . .