Reversibility of sodium-induced aggregation of sonicated phosphatidylserine vesicles.

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Abstract
The kinetics of Na-induced aggregation of sonicated phosphatidylserine vesicles was studied as a function of Na concentration and temperature. The concentration threshold for aggregation induced by monovalent sodium was found to be 550 mM Na by stopped-flow rapid-mixing techniques. This aggregation is completely reversible to changes in Na+ concentration and to changes in temperature. The aggregation rate decreases with increasing temperature, indicating that the backward reaction rate increases more rapidly with temperature than does the forward rate.

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