Oxidative Induction of β-Turn Conformations in Cyclic Peptidomimetics: Conformational Analyses As Indicators of Configuration
- 11 July 2002
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 124 (31) , 9028-9029
- https://doi.org/10.1021/ja0171411
Abstract
Solid-phase syntheses of the cyclic peptidomimetics 1−4 were performed. Sulfide 1 and sulfoxide 3 did not tend to exist in β-turn conformations in solution, but the sulfone 2 and the epimeric sulfoxide 4 did. The assignment of configuration of the sulfoxides is based on the conformational analyses.Keywords
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