Studies on complementation in argininosuccinate synthetase and argininosuccinate lyase deficiencies in human fibroblasts
- 1 May 1981
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 57 (3) , 282-284
- https://doi.org/10.1007/bf00278945
Abstract
Complementation tests after polyethylene glycol fusion have been performed between 10 citrullinemic strains with argininosuccinate synthetase deficiency and between five strains with argininosuccinate lyase deficiency. No complementation was observed between the citrullinemic strains, while two groups of complementation were defined with the argininosuccinate lyase deficients strains. Since the restoration of activity was not total, we assumed that complementation is probably intragenic.This publication has 15 references indexed in Scilit:
- Analysis of genetic complementation by whole-cell microtechniques in fibroblast heterokaryons.Proceedings of the National Academy of Sciences, 1979
- Studies of Rat Liver Argininosuccinate SynthetaseThe Journal of Biochemistry, 1979
- Argininosuccinase from bovine brain: Isolation and comparison of catalytic, physical, and chemical properties with the enzymes from liver and kidneyAnalytical Biochemistry, 1979
- Intergenic complementation after fusion of fibroblasts from different patients with β-galactosidase deficiencyBiochimica et Biophysica Acta (BBA) - Enzymology, 1979
- Argininosuccinic aciduria: assignment of the argininosuccinate lyase gene to the pter to q22 region of human chromosome 7 by bioautography.Proceedings of the National Academy of Sciences, 1978
- Chromosome assignment of a human gene for argininosuccinate synthetase expression in Chinese hamster X human somatic cell hybridsExperimental Cell Research, 1977
- Studies of Rat Liver Argininosuccinate SynthetaseThe Journal of Biochemistry, 1977
- A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and virusesNature, 1975
- Biosynthesis of urea. XIV. The quaternary structure of argininosuccinase.1972
- Argininosuccinase from bovine kidney: Comparison of catalytic, physical, and chemical properties with the enzyme from bovine liverArchives of Biochemistry and Biophysics, 1971