Molecular Machines
Open Access
- 8 January 2001
- journal article
- review article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 152 (1) , F1-F10
- https://doi.org/10.1083/jcb.152.1.f1
Abstract
The use of EM and image analysis techniques, particularly the single particle methodology, has opened the door to the structural characterization of large protein complexes in the megadalton range. This review covers the basic principles of single particle EM and recent examples of its applicationKeywords
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