Preliminary results of a phase I/II study With Pi-Meson (Pion) treatment for bladder cancer
- 15 October 1985
- Vol. 56 (8) , 1943-1952
- https://doi.org/10.1002/1097-0142(19851015)56:8<1943::aid-cncr2820560809>3.0.co;2-b
Abstract
Radiation therapy with negative pi-mesons (pions) was administered to 36 patients with bladder cancer. According to a Phase I/II study, doses varied from 3000 to 3600 pion rad. Although only two complete responses were achieved among 8 evaluable patients who had predominantly papillary bladder tumors, more promising results were obtained in 22 evaluable patients who had sessile, invasive carcinomas: 19 bladders were cystoscopically and cytologically cleared of tumor after 6 months. Although the side effects during the ambulatory treatment were minimal or tolerable, a steep dose-response curve for late side effects was observed with severe complications in 7 of 11 patients who received 3600 or more pion rad. Cancer 56: 1943-1952, 1985.This publication has 4 references indexed in Scilit:
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- The piotron: initial performance, preparation and experience with pion therapyInternational Journal of Radiation Oncology*Biology*Physics, 1982
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- Discouraging Results for High Dose External Beam Radiation Therapy in Low Stage (O and A) Bladder CancerJournal of Urology, 1982