Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
Top Cited Papers
- 1 April 2005
- Vol. 121 (2) , 257-270
- https://doi.org/10.1016/j.cell.2005.02.005
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- The Roles of Ribosomal Proteins in the Structure Assembly, and Evolution of the Large Ribosomal SubunitJournal of Molecular Biology, 2004
- Binding Site of Macrolide Antibiotics on the Ribosome: New Resistance Mutation Identifies a Specific Interaction of Ketolides with rRNAJournal of Bacteriology, 2001
- The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å ResolutionScience, 2000
- Erythromycin Resistance Mutations in Ribosomal Proteins L22 and L4 Perturb the Higher Order Structure of 23 S Ribosomal RNAJournal of Molecular Biology, 1999
- [20] Processing of X-ray diffraction data collected in oscillation modePublished by Elsevier ,1997
- Crystal Structures of 8-Cl and 9-Cl TIBO Complexed with Wild-type HIV-1 RT and 8-Cl TIBO Complexed with the Tyr181Cys HIV-1 RT Drug-resistant MutantJournal of Molecular Biology, 1996
- Erythromycin Binding is Reduced in Ribosomes with Conformational Alterations in the 23 S rRNA Peptidyl Transferase LoopJournal of Molecular Biology, 1993
- Functional analysis of seven ribosomal systems from extremely halophilic archaeaCanadian Journal of Microbiology, 1993
- Vernamycin BαActa Crystallographica Section C Crystal Structure Communications, 1990
- Interaction of vernamycin A with Escherichia coli ribosomesBiochemistry, 1971