Electronic Structure and Nicotine-like Stimulant Activity in Choline Phenyl Ethers
- 8 July 1960
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 132 (3419) , 87-89
- https://doi.org/10.1126/science.132.3419.87
Abstract
Frontier electron density at the ether oxygen position and superdelocalizability at the ortho position show good parallelism with biological activity—that is, the stimulant activity of phenyl ether choline molecules. The mechanism of the biological action is discussed in connection with this finding.Keywords
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