Covalent binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA
- 1 September 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 287 (5779) , 244-245
- https://doi.org/10.1038/287244a0
Abstract
Mouse embryo cells were exposed to one of the following carcinogens: 7,12-dimethylbenz[a]anthracene, s-methylcholanthrene, benzo[a]pyrene, 15,16-dihydro-11-methylcyclopenta[a]phenanthren-17-one, 15,16-dihydro-12-methylcyclopenta[a]phenanthren-17-one or benz[a]anthracene. Each of these polycyclic aromatic compounds bound with mitochondrial DNA 50-500 times more than with nuclear DNA.This publication has 20 references indexed in Scilit:
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