Is the Vidian Nerve Cholinergic?
- 1 July 1975
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 101 (7) , 422-425
- https://doi.org/10.1001/archotol.1975.00780360022005
Abstract
Electrical stimulation of the parasympathetic nerve (vidian) to the nasal mucosa induces a nasal secretion and a nasal vasodilation. We have provided additional evidence that, in the dog and cat, the secretory mechanism can be blocked with low doses of atropine sulfate (0.01 mg/kg), but the dilation mechanism is not blocked by high doses (1 mg/kg, of atropine sulfate. By some definitions therefore, the vasodilation is not a cholinergic effect. There appears to be a basic difference in the composition of the vidian nerve in the dog and cat. In the cat, the vidian appears to have a strong sympathetic component. In the dog it does not. The human vidian nerve, according to anatomists, is more like the dog's.Keywords
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