Atypical Fibroxanthoma
- 1 June 1985
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 121 (6) , 753-755
- https://doi.org/10.1001/archderm.1985.01660060067023
Abstract
• Fourteen biopsy specimens from ten patients with atypical fibroxanthoma were studied with the peroxidase-antiperoxidase method for binding of S-100 antibody. Six specimens from four patients were minimally positive. The S-100-positive cells were observed in greatest concentrations at the periphery of the lesions and were associated with perivascular inflammatory cells. By this method, it appears that there is not a Langerhans' cell type of atypical fibroxanthoma. The S-100 antibody can help differentiate desmoplastic juvenile melanoma and malignant melanoma from atypical fibroxanthoma. (Arch Dermatol1985;121:753-755)Keywords
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