HER-2/Neu signaling and therapeutic approaches in breast cancer

1 June 2002

journal article
Published by SAGE Publications in Breast Disease

Vol. 15 (1) , 13-24
https://doi.org/10.3233/bd-2002-15103

Abstract

Amplification or overexpression of HER-2/neu occurs in 30% of human breast and ovarian cancers and is associated with a poor clinical outcome, including short survival and time to relapse. Recent advances in our understanding of HER-2/neu signaling p

Keywords

SURVIVAL
2/NEU SIGNALING
POOR
RELAPSE
OVARIAN
OVEREXPRESSION
THERAPEUTIC APPROACHES
APPROACHES IN BREAST
SIGNALING AND THERAPEUTIC

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