HIV Protease Inhibitors Possessing a Novel, High-Affinity, and Achiral P1'/P2' Ligand with a Unique Pattern of in Vitro Resistance. Importance of a Conformationally-Restricted Template in the Design of Enzyme Inhibitors
- 1 November 1995
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 117 (45) , 11070-11074
- https://doi.org/10.1021/ja00150a005
Abstract
No abstract availableThis publication has 7 references indexed in Scilit:
- Asymmetric Synthesis of an HIV Protease Inhibitor via a Novel .alpha.-Oxoketene/Ketene [4 + 2] Cycloaddition ReactionJournal of the American Chemical Society, 1994
- The cost of conformational order: entropy changes in molecular associationsJournal of the American Chemical Society, 1992
- Molecular Targets for AIDS TherapyScience, 1990
- A Synthetic HIV-1 Protease Inhibitor with Antiviral Activity Arrests HIV-Like Particle MaturationScience, 1990
- Mechanism by which warfarin binds to human serum albuminBiochemical Pharmacology, 1989
- STRUCTURAL REQUIREMENTS FOR DRUG-BINDING TO SITE-II ON HUMAN-SERUM ALBUMIN1983
- Clinical Pharmacokinetics of Oral AnticoagulantsClinical Pharmacokinetics, 1979