Effect of Bisphenol A on the Feeding Behavior of Caenorhabditis elegans.
- 1 January 2002
- journal article
- Published by Pharmaceutical Society of Japan in Journal of Health Science
- Vol. 48 (1) , 93-95
- https://doi.org/10.1248/jhs.48.93
Abstract
We observed and evaluated the feeding behavior of the free-living nematode Caenorhabditis elegans (C. elegans) after exposure to bisphenol A (BPA) and nonylphenol (NP). Exposed organisms were transferred to chemical-free culture medium and their attainment levels (the number of worms reaching the food source divided by the total number of worms on the Petri plate) were recorded after 2, 4, 6, 8, and 24 hr. Results showed a significant decrease in the attainment level of worms exposed to 10 μM and 0.1 μM BPA. However, there was a slight increase in the attainment level of nematodes treated with 1 μM NP. These results differ from previous studies showing NP as being more lethal to nematodes than BPAKeywords
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