Reversible IgA deficiency in hypothyroidism
- 1 November 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in Postgraduate Medical Journal
- Vol. 57 (673) , 714-716
- https://doi.org/10.1136/pgmj.57.673.714
Abstract
Summary: A 50-year-old woman developed pronounced IgA-deficiency and hypothyroidism after 131I treatment for Graves’ disease. The deficiency state was associated with a severe sinobronchial syndrome. Treatment with L-thyroxine resulted in a normal IgA concentration and a dramatic clinical improvement. Of the various possible underlying mechanisms, impaired synthesis of IgA light and heavy light chains seemed most probable. Impaired production of J-chain was excluded.This publication has 6 references indexed in Scilit:
- CLINICAL FINDINGS AND INTESTINAL IMMUNOGLOBULINS IN CHILDREN WITH PARTIAL IgA DEFICIENCYActa Paediatrica, 1979
- Quantitation of J Chain in Human Biological Fluids by a Simple Immunochemical ProcedureActa Medica Scandinavica, 1978
- Effect of Antiepileptic Drugs on Serum and Salivary IgAScandinavian Journal of Immunology, 1975
- Studies on the Serum γA-Globulin Level III. The Frequency of A-γA-GlobulinemiaScandinavian Journal of Clinical and Laboratory Investigation, 1965