Plasma Corticosterone and Cardiac Glycogen Levels in Rats after Exercise

Publisher Website
Google Scholar
Abstract
There is an increase in both plasma corticosterone and myocardial glycogen following exercise although the peak in plasma glucocorticoids is relatively brief. A 4-h interval between the peaks in plasma glucocorticoid and myocardial glycogen levels appears appropriate for a cause and effect relationship since glucocorticoid administration takes approximately 4 h to significantly increase either cardiac glycogen or liver glycogen. The association between steroids and myocardial glycogen recovery following exercise is still somewhat dubious; since chronic treatment with a potent glucocorticoid (dexamethasone) is as effective as a burst of corticosterone (control rats) in permitting the observed pattern of cardiac glycogen supercompensation. This suggests that physical exertion and the presence of steroids (i.e., a permissive effect of glucocorticoid rather than a causative one) can produce changes, perhaps local, that are influential on cardiac glycogen for hours following exercise.

This publication has 0 references indexed in Scilit: