Evaluation of the osmotic effects of glucose loads in food satiation.

Publisher Website
Google Scholar
Abstract
Osmotic theories of food intake predict that ingestion of hypertonic glucose and NaCl should concomitantly produce food satiety and thirst. Twenty-four rats were tested after ad-lib feeding and 22-hours food deprivation. Two hr. food- and water-intake tests followed stomach loads of sham intubation, or 3% body weight of water, 1[image] glucose, or 5 [image] NaCl. Hunger increased all intakes without interacting with loads. Water, a known hydrator, decreased water intake without changing food intake. NaCl, a known dehydrator, decreased food and increased water intake. Glucose decreased food intake but also decreased water intake. NaCl satiety may be osmotic, but glucose, acting like a hydrator rather than a dehydrator, satiates via a metabolic rather than a colligative route.

This publication has 2 references indexed in Scilit: