AKT-Independent Signaling Downstream of Oncogenic PIK3CA Mutations in Human Cancer
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- 1 July 2009
- journal article
- research article
- Published by Elsevier in Cancer Cell
- Vol. 16 (1) , 21-32
- https://doi.org/10.1016/j.ccr.2009.04.012
Abstract
No abstract availableKeywords
This publication has 64 references indexed in Scilit:
- Identification of Flightless-I as a Substrate of the Cytokine-independent Survival Kinase CISKJournal of Biological Chemistry, 2009
- Knockin of mutant PIK3CA activates multiple oncogenic pathwaysProceedings of the National Academy of Sciences, 2009
- A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibitionBiochemical Journal, 2008
- Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesisNature, 2008
- A transforming mutation in the pleckstrin homology domain of AKT1 in cancerNature, 2007
- Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activityProceedings of the National Academy of Sciences, 2007
- A collection of breast cancer cell lines for the study of functionally distinct cancer subtypesCancer Cell, 2006
- CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4The EMBO Journal, 2006
- The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolismNature Reviews Genetics, 2006
- BRAF mutation predicts sensitivity to MEK inhibitionNature, 2005