The LRRK2 gene in Parkinson's disease: mutation screening in patients from Germany
- 20 March 2006
- journal article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 77 (7) , 891-892
- https://doi.org/10.1136/jnnp.2005.083022
Abstract
Some questions remain about the growing demand of DNA diagnostics and genetic counselling in Parkinson’s disease. Which subpopulation of patients with Parkinson’s disease harbours the highest risk of mutations in the LRRK2 gene? What is the frequency and penetrance of different LRRK2 mutations? Nine exons (exons 19, 24, 25, 29, 31, 34, 35, 38 and 41) of the LRRK2 gene were screened for sequence …Keywords
This publication has 5 references indexed in Scilit:
- Altered α-synuclein homeostasis causing Parkinson's disease: the potential roles of dardarinTrends in Neurosciences, 2005
- Escaping Parkinson's disease: A neurologically healthy octogenarian with the LRRK2 G2019S mutationMovement Disorders, 2005
- A common LRRK2 mutation in idiopathic Parkinson's diseaseThe Lancet, 2005
- Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's DiseaseNeuron, 2004
- Protein Kinases Linked to the Pathogenesis of Parkinson's DiseaseNeuron, 2004