The siphon controversy: an integration of concepts and the brain as baffle
- 1 August 2005
- journal article
- Published by American Physiological Society in American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Vol. 289 (2) , R627-R629
- https://doi.org/10.1152/ajpregu.00709.2004
Abstract
Using a model of both rigid and collapsible tubes, Hicks and Badeer (10) reported that the siphon mechanism is still operating within vertically oriented models, even when the descending limb is flexible and partly collapsed (10). This implies that partially collapsed descending veins do not interrupt the siphon as long as there is a continuous column of fluid. They emphasize the importance of the interaction of the viscous and the hydrostatic components in the interpretation of pressure measurements in a vessel. They attribute the pressure gradient of 13 to 4 mmHg down the jugular veins of a standing giraffe (9), where approximately −93 to −27 mmHg would be expected based solely on the prevailing hydrostatic gradient, as related to the sum of gravitational and viscous pressures. In a more recent study, the authors further support the concept that the heart does not have to overcome the weight of the blood pumped to the head, only the viscous resistance of the blood vessels (11). They state that the mechanical advantage of a closed system in relation to gravitational effects is similar to the operation of the loop of a siphon, but to avoid confusion of the physics of open vs. closed systems, the term “siphon” should be avoided: “in ‘open' systems, gravity hinders uphill flow and causes downhill flow, in which the liquid acts as a falling body. In contrast, in ‘closed' systems, like the circulation, gravity does not hinder uphill flow, nor does it cause downhill flow, because gravity acts equally on the ascending and descending limbs of the circuit” (11). Bearing in mind the difference between open vs. closed systems, for historical reasons, we will continue to use the term “siphon” here.Keywords
This publication has 15 references indexed in Scilit:
- Human cerebral venous outflow pathway depends on posture and central venous pressureThe Journal of Physiology, 2004
- Standing up to the challenge of standing: a siphon does not support cerebral blood flow in humansAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2004
- How does the blood leave the brain? A systematic ultrasound analysis of cerebral venous drainage patternsNeuroradiology, 2004
- Gravity and the circulation: "open" vs. "closed" systemsAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1992
- Hemodynamics of vascular ‘waterfall’: is the analogy justified?Respiration Physiology, 1992
- Snakes, Blood Circulation and GravityScientific American, 1988
- Gravitational haemodynamics and oedema prevention in the giraffeNature, 1987
- Venous pressure changes during orthostasisCardiovascular Research, 1972
- The Vertebral Venous Plexus as a Major Cerebral Venous Outflow TractAnesthesiology, 1970
- The Influence of the Force of Gravity on the CirculationThe Journal of Physiology, 1897