Solid phase enzyme immunoassay of tobramycin.

Abstract
A competitive enzyme immunoassay (EIA) using co-polymer of styrene and maleate as the solid phase and glutaraldehyde for binding of the antibody to the solid phase was developed. This assay showed a striking efficacy in its use for the assay of tobramycin (TOB). The pharmacokinetics of TOB were studied in 6 healthy male volunteers after the administration of 60- or 90-mg doses i.m.

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