Acid-catalyzed Exchange at 250 °C; a Simple and Quantitative Method for the Replacement of Aromatic Protons by Deuterium

1 May 1973

journal article
Published by Canadian Science Publishing in Canadian Journal of Chemistry

Vol. 51 (9) , 1485-1486
https://doi.org/10.1139/v73-224

Abstract

Treatment of benzene (1), biphenyl (2) and o- and m-xylene (3 and 4) with 4% v/v concentrated HCl (concentrated DCl) in D₂O at 250 °C results in selective deuteration of the aromatic nucleus with excellent isotopic incorporation and quantitative yield.

Keywords

TREATMENT
REPLACEMENT
XYLENE
DEUTERIUM
BENZENE
DCL
HCL
PROTONS
V/V
ISOTOPIC

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