A comparison of oxytetracycline and trimethoprim in the treatment of chlamydia trachomatis urethritis

Abstract
Summary The effect of trimethoprim was compared with that of oxytetracycline in the treatment of uncomplicated urethritis and/or cervicitis. Twenty-six patients treated with oxytetracycline were all microbiologically cured. Of 19 patients treated with trimethoprim, ten (53%) still harboured the chlamydia after two weeks. The superiority of tetracycline was even more pronounced following the evaluation of dysuria and discharges. 85% of the patients treated with oxytetracycline and 6% of those treated with trimethoprim had neither dysuria nor discharge after the completion of treatment. The patients who failed to be cured by trimethoprim were all successfully treated with oxytetracycline.