Free and bound choline blood levels after phosphatidylcholine

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Abstract
In 6 normal subjects the effects of oral phosphatidylcholine (lecithin) on the concentrations of plasma choline, erythrocyte choline and choline-containing lipids, were investigated. Plasma choline levels rose 1 h after treatment and remained elevated for 8 h, with peaks at 3 and 4 h after phosphatidylcholine. Erythrocyte choline levels also rose, although the rise was slightly delayed relative to plasma choline. There was no change in the plasma choline-containing lipid concentration. In normal subjects, oral phosphatidylcholine induces prolonged rises in plasma and erythrocyte choline concentrations and is therefore useful when such effects are desired.