Why “underpowered” trials are not necessarily unethical
- 1 September 1997
- journal article
- Published by Elsevier in The Lancet
- Vol. 350 (9080) , 804-807
- https://doi.org/10.1016/s0140-6736(97)02290-3
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- Explanatory and pragmatic attitudes in therapeutical trialsPublished by Elsevier ,2004
- “Meta-analysis: Statistical alchemy for the 21st century”: Discussion. A plea for a more balanced view of meta-analysis and systematic overviews of the effect of health care interventionsJournal of Clinical Epidemiology, 1995
- Towards an International Register of Cancer Trials: The UKCCCR register of U.K. trialsEuropean Journal Of Cancer, 1993
- The role ofP‐values in analysing trial resultsStatistics in Medicine, 1993
- Can meta-analyses be trusted?The Lancet, 1991
- Must clinical trials be large? The interpretation of p‐values and the combination of test resultsStatistics in Medicine, 1990
- The Alpha and Beta Errors in Randomized TrialsNew England Journal of Medicine, 1990
- Size of trials for evaluation of antenatal tests of fetal wellbeing in high risk pregnancyjpme, 1990
- Evaluating New Treatments and Diagnostic Technologies in Obstetrics: Practical Problems, Ethics, and SolutionsInternational Journal of Technology Assessment in Health Care, 1989
- Statistics and ethics in medical research: III How large a sample?BMJ, 1980