Preparation of blood globin through carboxymethyl cellulose chromatography

Abstract
Summary: A simple and inexpensive procedure for globin preparation from blood of various animals was developed in order to use globin as human food. Carboxymethyl cellulose was most effective among some cation exchangers tested, although amounts of haemoglobin applied to 1 g of the exchanger should be limited to less than 70 mg. The behaviour of adsorbing haem or haemin to the exchanger could not be explained only by a general theory of ion exchange chromatography. Yields and Fe contents of globin preparations from various haemoglobins by this procedure ranged from 67 to 80% and from 0.008 to 0.03% respectively, except for a chicken haemoglobin sample.

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