The Natural History of Spine Curvature Progression in the Nonambulatory Duchenne Muscular Dystrophy Patient

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Abstract
The natural progression of the spinal curve of 8 nonambulatory Duchenne Muscular Dystrophy (DMD) patients were followed from 38-91 mo. (average, 5 yr and 2 mo.). Curve progression was seen in all patients. In patients whose curves exceeded 40.degree., secondary complications, including loss of function, diminished sitting tolerance, use of the arms and hands to prop the body up when seated, pain and a diminished vital capacity (12-16%), were present.

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