Antagonism of Ethanol Narcosis in Mice by Hyperbaric Pressures of 4–8 Atmospheres
- 1 October 1980
- journal article
- Published by Wiley in Alcohol, Clinical and Experimental Research
- Vol. 4 (4) , 350-353
- https://doi.org/10.1111/j.1530-0277.1980.tb04830.x
Abstract
Hyperbaric treatment with 100% oxygen or oxygen‐helium mixtures at 4–8 atmospheres absolute significantly reduced ethanol sleep‐time and increased wake‐up blood ethanol concentrations in C57 mice. The results indicate that the antagonsim does not result from direct effects of oxygen nor from enhanced ethanol elimination, but appears to involve a direct effect of hyper‐baric treatment.Keywords
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