MORPHOLOGY AND DNA CONTENT OF ENDOMETRIAL CANCER NUCLEI UNDER PROGESTOGEN TREATMENT

1 January 1976

journal article
research article

Vol. 20 (6) , 556-558

Abstract

Twelve human endometrial cancers were observed before and during progestogen treatment. Eight were well differentiated and displayed an objective response. It was essentially characterized by a volumeric reduction of the nucleus and the disappearance of tetraploid nuclei. The DNA content remained diploid or near diploid. Reduction of nuclear non-DNA proteins under hormonal treatment is suggested.

Keywords

BIOLOGY
CANCER
CLINICAL RESEARCH
CYTOLOGIC EFFECTS
DISEASES
ENDOCRINE SYSTEM
ENDOMETRIAL CANCER
GENITALIA
GENITALIA, FEMALE
HORMONES
NEOPLASMS
PHYSIOLOGY
PROGESTATIONAL HORMONES
PROGESTERONE--SIDE EFFECTS
PROGESTERONE--THERAPEUTIC USE
RESEARCH METHODOLOGY
UROGENITAL SYSTEM
UTERUS

This publication has 1 reference indexed in Scilit:

Deoxyribonucleic acid content of presumed precursors of endometrial carcinoma
Cancer, 1967