The Biology of Oxygen Radicals
- 8 September 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 201 (4359) , 875-880
- https://doi.org/10.1126/science.210504
Abstract
The reactive superoxide radical, O 2 - , formerly of concern only to radiation chemists and radiobiologists, is now understood to be a normal product of the biological reduction of molecular oxygen. An unusual family of enzymes, the superoxide dismutases, protect against the deleterious actions of this radical by catalyzing its dismutation to hydrogen peroxide plus oxygen.This publication has 67 references indexed in Scilit:
- Superoxide‐dependent production of hydroxyl radical catalyzed by iron—EDTA complexFEBS Letters, 1978
- An attempt to demonstrate a reaction between superoxide and hydrogen peroxideFEBS Letters, 1976
- Isolation of a new copper — Containing superoxide dismutase bacteriocupreinBiochemical and Biophysical Research Communications, 1974
- Effects of superoxide radicals on myoblast growth and differentiationBiochemical and Biophysical Research Communications, 1974
- Superoxide radicals as precursors of mitochondrial hydrogen peroxideFEBS Letters, 1974
- The mechanism of the oxidation of ascorbate and Mn2+ by chloroplasts: The role of the radical superoxideBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1973
- The valence of copper and the role of superoxide in the D-galactose oxidase catalyzed reactionBiochemical and Biophysical Research Communications, 1973
- Biological protection by superoxide dismutaseBiochemical and Biophysical Research Communications, 1973
- Catalytic Mechanism of Cytochrome OxidaseNature, 1970
- Direct demonstration of superoxide anion production during the oxidation of reduced flavin and of its catalytic decomposition by erythrocupreinBiochemical and Biophysical Research Communications, 1969