IMPROMIDINE (SK&F 92676) ACTS AS A PARTIAL AGONIST ON THE ISOLATED WHOLE STOMACH OF THE RAT
Open Access
- 1 May 1980
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 69 (1) , 6-7
- https://doi.org/10.1111/j.1476-5381.1980.tb10874.x
Abstract
The present secretory studies on the isolated stomach of the rat provide evidence that impromidine acts as a partial agonist at the histamine H2-receptors. It was found to be 100 times more potent than histamine but with a maximal response only 50% that obtained with histamine.Keywords
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