Long‐term Hypotensive Effect of Atenolol (ICI 66.082), a New β‐adrenergic Blocking Agent

Abstract
This is a report from an on-going multicenter trial in Sweden, in which 117 hypertensive patients were treated with a new cardioselective .beta.-adrenergic blocking agent, atenolol (ICI 66.082, Tenormin) for an average of 6 mo. (range 2-21). Statistically significant reductions of BP [blood pressure] were observed, recumbent by 29/19 mmHg (p < 0.0001) and standing by 28/18 mmHg (p < 0.0001). Few and comparatively mild side-effects were seen.