Fatty Acid Distributions in Serum Lipids and Serum Lipoproteins

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Abstract
Gas-liquid chromatographic studies of each of the principal fatty acid-containing serum lipid fractions (cholesteryl esters, glycerides, unesterified fatty acids and phospholipids) reveal a relatively characteristic fatty acid pattern. Some variability, particularly in the cholesteryl ester fatty acid distribution, exists from person to person. In any given subject, the principal fatty acid-containing lipid fractions isolated from each of the major serum lipoprotein classes appear similar with one exception. Our preliminary data suggest the cholesteryl ester fraction of the sf° 20–105 lipoproteins contain a higher content of oleic and palmitic acid as well as a lower content of linoleic acid relative to the cholesteryl ester fractions obtained from the sf° 0–20 and HDL-2 and 3 lipoprotein classes.