LYSOZYME TEAR LEVEL IN PATIENTS WITH HERPES-SIMPLEX VIRUS EYE INFECTION

1 January 1977

journal article
research article

Vol. 16 (9) , 850-852

Abstract

The lysozyme level in tears of patients with HSV [herpes simplex virus] eye infection was examined and correlated with the clinical findings and presence of virus. The concentration of the enzyme in tears of patients during acute attack was 2.83 mg/ml. This value was significantly lower than that in tears from healthy controls (6.1 mg/ml) and in tears from the patient''s healthy eye (4.46 mg/ml). After termination of treatment with IUDR [5-iodo-2-deoxyuridine] or poly I:C, the lysozyme level rose to an average of 4.34 mg/ml. During the latent period of the disease the level increased (5.34 mg/ml), but it remained lower than in healthy subjects who never suffered from HSV eye infection. This may be an indicator of possible future recurrences.

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