Childhood Adversities and Adult Psychiatric Disorders in the National Comorbidity Survey Replication I

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Abstract
Significant associations between retrospectively reported childhood adversities (CAs) and adult illness have been documented in numerous studies.1,2 The first such studies focused on only a single CA, such as parental death or neglect,3,4 and 1 mental disorder, most often depression.5,6 Subsequent studies showed that retrospectively reported CAs are often highly clustered,7,8 requiring examination of multiple CAs to avoid overestimating associations involving particular CAs.2,9,10 These studies also found that CAs are often nonspecific in their associations with many different mental disorders,10-12 making it useful to examine multiple outcomes to avoid overly narrow interpretations.