A structural perspective of the flavivirus life cycle
Top Cited Papers
- 1 January 2005
- journal article
- review article
- Published by Springer Nature in Nature Reviews Microbiology
- Vol. 3 (1) , 13-22
- https://doi.org/10.1038/nrmicro1067
Abstract
Dengue, Japanese encephalitis, West Nile and yellow fever belong to the Flavivirus genus, which is a member of the Flaviviridae family. They are human pathogens that cause large epidemics and tens of thousands of deaths annually in many parts of the world. The structural organization of these viruses and their associated structural proteins has provided insight into the molecular transitions that occur during the viral life cycle, such as assembly, budding, maturation and fusion. This review focuses mainly on structural studies of dengue virus.Keywords
This publication has 95 references indexed in Scilit:
- Conformational change and protein–protein interactions of the fusion protein of Semliki Forest virusNature, 2004
- DC-SIGN (CD209) Mediates Dengue Virus Infection of Human Dendritic CellsThe Journal of Experimental Medicine, 2003
- Placement of the Structural Proteins in Sindbis VirusJournal of Virology, 2002
- The Fusion Glycoprotein Shell of Semliki Forest VirusCell, 2001
- Heparan Sulfate Proteoglycans Initiate Dengue Virus Infection of HepatocytesHepatology, 2000
- The envelope glycoprotein from tick-borne encephalitis virus at 2 Å resolutionNature, 1995
- Analysis of virus-cell binding characteristics on the determination of Japanese encephalitis virus susceptibilityArchiv für die gesamte Virusforschung, 1994
- Tick-borne encephalitis virus interaction with the target cellsArchiv für die gesamte Virusforschung, 1992
- Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolutionNature, 1981
- Physical Principles in the Construction of Regular VirusesCold Spring Harbor Symposia on Quantitative Biology, 1962