Interferon Induces Natural Killer Cell Blastogenesis In Vivo
- 1 January 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Leukocyte Biology
- Vol. 35 (1) , 31-37
- https://doi.org/10.1002/jlb.35.1.31
Abstract
Interferon (IFN), types beta and gamma, and IFN inducers polyinosinic-polycytidylic acid and lymphocytic choriomeningitis virus all stimulated the generation of blast-NK cells in mouse spleens. Blast-NK cells were characterized on the basis of size, 3H-thymidine uptake, and NK cell markers. These data indicate that in addition to augmenting NK cell-mediated lysis, IFN may regulate NK cell proliferation in vivo.This publication has 22 references indexed in Scilit:
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