Abstract
The normal development of the first lower molar of the rat has been described from the 13th day of foetal life to the 2d day after birth and of the lower temporary molars of the rabbit from the 15th to the 26th day of foetal life. Molar tooth germs of the rat and rabbit when cultivated in vitro showed remarkable powers of anatomical and histological development. The tooth germs explanted before cusps had appeared formed cusps which were almost normal in shape, number, and arrangement, odontoblasts and dentine differentiated and the internal enamel epithelium of rabbit tooth germs differentiated into ameloblasts which formed enamel.

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