Current management of melanoma: Benefits of surgical staging and adjuvant therapy
- 26 February 2003
- journal article
- review article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 82 (3) , 209-216
- https://doi.org/10.1002/jso.10216
Abstract
Issues regarding appropriate management of stage I to III melanoma are addressed. Accurate surgical staging is critical to identifying patients who can benefit from therapeutic lymph node dissection and adjuvant therapy. Patients with primary tumors ≥1 mm thick are appropriate candidates for sentinel lymph node biopsy, and node‐positive patients benefit from therapeutic lymphadenectomy. Although the overall survival benefit of high‐dose interferon has been questioned, the weight of evidence supports the use of adjuvant therapy in patients with stage IIB and III disease. J. Surg. Oncol. 2003;82:209–216.Keywords
This publication has 49 references indexed in Scilit:
- Improved Staging of Node-Negative Patients With Intermediate to Thick Melanomas (>1 mm) With the Use of Lymphatic Mapping and Sentinel Lymph Node BiopsyAnnals of Surgical Oncology, 2001
- Sentinel Lymph Node Biopsy for Melanoma: How Many Radioactive Nodes Should be Removed?Annals of Surgical Oncology, 2001
- Role for Surgical Cytoreduction in Multimodality Treatments for CancerAnnals of Surgical Oncology, 2001
- Long-Term Results of a Multi-Institutional Randomized Trial Comparing Prognostic Factors and Surgical Results for Intermediate Thickness Melanomas (1.0 to 4.0 mm)Annals of Surgical Oncology, 2000
- Adjuvant trial in melanoma patients comparing rIFN-α to rIFN-γ to Iscador to a control group after curative resection of high risk primary (≥3 MM) or regional lymphnode metastasis (EORTC 18871)European Journal Of Cancer, 1999
- Adjuvant IFNα2 therapy of melanomaThe Lancet, 1998
- Immediate or delayed dissection of regional nodes in patients with melanoma of the trunk: a randomised trialThe Lancet, 1998
- Surgical management of primary cutaneous melanomaCA: A Cancer Journal for Clinicians, 1996
- The incidence of malignant melanoma in the United States: Issues as we approach the 21st centuryJournal of the American Academy of Dermatology, 1996
- Thin Stage I Primary Cutaneous Malignant MelanomaNew England Journal of Medicine, 1988