Reactive (secondary) amyloidosis and its pathogenesis
- 1 January 1984
- journal article
- review article
- Published by Springer Nature in Rheumatology International
- Vol. 5 (1) , 1-7
- https://doi.org/10.1007/bf00541358
Abstract
Recent advances in amyloid research have broadened our understanding of amyloidogenesis in connection with chronic inflammatory and infectious conditions. Experimental and clinical studies have clarified many of the mechanisms of induction, synthesis and regulation of the amyloid-related serum component SAA and have shed light on the enzymatic processes involved in the cleavage of SAA and degradation of fibrillar AA protein. The current pathogenetic model emphasizes the dynamic character of amyloid disease.Keywords
This publication has 107 references indexed in Scilit:
- Is Interferon an Inducer of Serum Amyloid A?New England Journal of Medicine, 1983
- Stimulation of Muscle Protein Degradation and Prostaglandin E2Release by Leukocytic Pyrogen (Interleukin-1)New England Journal of Medicine, 1983
- Muscle Proteolysis Induced by a Circulating Peptide in Patients with Sepsis or TraumaNew England Journal of Medicine, 1983
- Amyloid Production in Human Myeloma Stem-Cell Culture, with Morphologic Evidence of Amyloid Secretion by Associated MacrophagesNew England Journal of Medicine, 1982
- The heterogeneity of protein AA in secondary (reactive) systemic amyloidosisBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982
- Induction of hepatic synthesis of serum amyloid A protein and actin.Proceedings of the National Academy of Sciences, 1981
- Amyloid Deposits and AmyloidosisNew England Journal of Medicine, 1980
- The complete amino acid sequence of an amyloid fibril protein AA1 of unusual size (64 residues)Biochemical and Biophysical Research Communications, 1976
- An amyloid protein: The amino-terminal variable fragment of an immunoglobulin light chainBiochemical and Biophysical Research Communications, 1970
- Human amyloid protein: Diversity and uniformityBiochemical and Biophysical Research Communications, 1970