Group-Specific Component (Gc): Subtypes in the Finnish Population
- 1 January 1986
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 36 (5) , 299-303
- https://doi.org/10.1159/000153646
Abstract
The group-specific component (Gc) subtypes were determined in 575 adult Finns by immunoblotting after isoelectric focusing in agarose gel. The gene frequencies were Gc1S = 0.661, Gc1F = 0.139 and Gc2 = 0.200. This material included one rare allele, a more acidically focusing Gc 2 (named Gc 2A18). The phenotypes of 200 mother-child pairs studied were in accordance with the three-allelic mode of inheritance. An apparent mother-child incompatibility observed during routine paternity testing is reported.Keywords
This publication has 8 references indexed in Scilit:
- Serum vitamin D-binding protein is a third member of the albumin and alpha fetoprotein gene family.Journal of Clinical Investigation, 1985
- Human group-specific component (Gc) is a member of the albumin family.Proceedings of the National Academy of Sciences, 1985
- A Silent Transferrin Allele in a Finnish FamilyHuman Heredity, 1984
- Phosphoglucomutase (PGM1) Subtypes in a Finnish Population Determined by Isoelectric Focusing in Agarose GelHuman Heredity, 1984
- The polymorphism of the vitamin D-binding protein (Gc); Isoelectric focusing in 3 M urea as additional method for identification of genetic variantsHuman Genetics, 1983
- A deficiency mutant of the Gc systemHuman Genetics, 1983
- Group-Specific Component: Evidence for two Subtypes of the Gc 1 GeneScience, 1977
- Possible Localization of Gc-System on Chromosome 4. Loss of Long Arm 4 Material Associated with Father-Child Incompatibility Within the Gc-SystemHuman Heredity, 1977